Considering JYNARQUE

Some things to think about when considering JYNARQUE® (tolvaptan)

Are you committed to taking action? Talk to your doctor about the progression of your ADPKD.

If you are at risk for fast progressing ADPKD, JYNARQUE might help change the course of your disease by slowing the decline of kidney function.

See what JYNARQUE can do here.

How will a regular blood test fit into your schedule? To take JYNARQUE, you and your doctor will need to monitor your liver health together.

  • In studies, 5% of patients (1 in 20) had signs of liver injury while taking JYNARQUE. If this happens to you, your doctor might ask you to stop taking JYNARQUE.
  • If you don’t think you can get to a lab or doctor’s office for a blood test once a month, JYNARQUE may not be right for you

Will you be able to deal with the common side effects?

JYNARQUE may cause excessive thirst and urination. These side effects are related to how JYNARQUE works in the kidneys. 75% of patients who made it to 3 years with JYNARQUE in clinical studies said they could keep taking their current dose for as long as their doctor tells them to.

Questions to ask yourself:

  • Will you be able to drink more water throughout the day?
  • Are you able to stick to a schedule when it comes to taking your medicine?
  • Are you prepared to make some lifestyle changes to account for increased urination?

In clinical studies, JYNARQUE wasn’t right for everyone.

  • 8% of people taking JYNARQUE had to stop because of these common side effects, but most people continued taking it.

Are you starting or currently taking JYNARQUE but can't make it to your required labwork?

We will come to you.

Learn more



To help, we are offering a Home Collection Service available to all current, eligible patients taking JYNARQUE. A phlebotomist will be sent to your home to collect a blood sample for your REMS*-required blood work. The collection and processing will be free of charge to you.


If you are interested in this service, please reach out to your prescribing physician directly to get more details on this program or contact the Otsuka Patient Support Center at 1-855-242-7787 who are available from 9AM to 5PM EST.

*Risk Evaluation and Mitigation Strategy

Learn more