JYNARQUE® (tolvaptan) may help change the course of your disease
JYNARQUE is the first and only FDA-approved treatment proven to slow kidney function decline in adults who are at risk for rapidly progressing autosomal dominant polycystic kidney disease (ADPKD).
JYNARQUE slows the decline in kidney function
Data from a 1-year clinical study of patients with chronic kidney disease (CKD) stages 2 to 4
*Kidney function or estimated glomerular filtration rate (eGFR) is measured in units of mL/min/1.73 m2.
Data from a 3-year clinical study of patients with CKD stages 1 to 3
*Kidney function or eGFR is measured in units of mL/min/1.73 m2.
JYNARQUE is proven to slow kidney function decline in adults who are at risk for rapidly progressing ADPKD.
Patients taking JYNARQUE had less kidney pain
In a clinical trial of ADPKD patients with CKD stages 1 to 3, patients taking JYNARQUE had
36% fewer pain events
requiring medication or other treatment than those taking placebo.
Treatment was defined as:
- Prescribed leave
- Radiologic treatment
JYNARQUE works at different stages of the disease
JYNARQUE is for adults at risk of having rapidly progressing ADPKD. With JYNARQUE, you may be able to slow the progression of your disease—at any stage of CKD.
JYNARQUE works across CKD stages 1 to 4
JYNARQUE is not for everyone. Ask your doctor to see if JYNARQUE is right for you.
JYNARQUE is a long-term treatment that has been studied in many patients
- JYNARQUE is a proven treatment that has been studied in over 3000 people with ADPKD, and prescribed to over 5500 people
- JYNARQUE may change the course of your disease by slowing kidney function decline as it works over a period of years. As you take JYNARQUE, remember that it is a long-term treatment and it may take time to see a difference
Start slowing your disease progression with JYNARQUE. Talk to your doctor to see if JYNARQUE is the right treatment option for you.
Please read IMPORTANT SAFETY INFORMATION for JYNARQUE, including BOXED WARNING and MEDICATION GUIDE, below.
How JYNARQUE works
How does JYNARQUE work?
JYNARQUE works by blocking a hormone that can cause cysts to grow in people with ADPKD.
For illustrative purposes only.